IVF-M HP Adverse Reactions

1) Skin: a local reaction at the injection site (pain, itchiness, swelling or redness), rash, anaphylaxis, shock, acne.
2) Hypersensitivity: urticaria, facial edema, angioneurotic edema, and dyspnea from laryngeal edema may occur.
3) Genitourinary: OHSS, multiple pregnancy, ovarian enlargement, ovarian cyst, breast pain, ovarian torsion.
4) Cardiovascular: Cerebral thrombosis, thromboembolism, hypotension, hemoconcentration, tachycardia.
5) Respiratory: Hydrothorax, dyspnea, tachypnea.
6) Gastrointestinal: Nausea, vomiting, diarrhea, abdominal cramps, abdominal distension, abdominal pain, abdominal discomfort.
7) Nervous system: Dizziness, headache, malaise.
8) Others: Abortion, pyrexia, pelvic pain, arthralgia, lower abdominal pain, ascites, oliguria, occasional pain after treatment, long-term use of menotrophin can lead to the formation of antibodies in very rare cases, excessive increase of serum estradiol levels (If there is any steep rise in values, treatment should be immediately discontinued and hCG withheld), hemoperitoneum, fatigue, musculoskeletal pain, facial blush (hot flush), visual disorders.